Max Planck Florida Institute for Neuroscience

Max Planck Florida Institute for Neuroscience

Focus on Neural Circuits

Understanding the functional organization of the nervous system, its capacity to produce perception, thought, language, memory, emotion, and action, remains the ultimate challenge for biology. Neural circuits, the complex synaptic networks of the brain, hold the key to understanding who we are, why we behave the way we do, and how the debilitating effects of neurological and psychiatric disorders can be ameliorated. Meeting this challenge requires forging links between different levels of analysis—genetic, molecular, cellular, circuit, and behavioral—and developing new technologies that make cutting edge scientific discoveries possible. The Max Planck Florida Institute brings together outstanding scientists with a broad range of expertise in a cohesive, collaborative environment designed to stimulate the development of novel approaches to understanding the structure, function, and development of neural circuits.

Part of the prestigious Max Planck Society based in Germany, the MPFI is the first and only institute of its kind in North America. Situated in the new biosciences cluster in scenic Palm Beach County in south Florida, the MPFI provides a vibrant, interactive environment where scientists are provided generous ongoing support to conduct high impact research at the cutting edge.

 

Latest Publications from each Research Group


Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

Dr. Ryohei Yasuda - July 8, 2014

Cdc42 is a signaling protein important for reorganization of actin cytoskeleton and morphogenesis of cells. However, the functional role of Cdc42 in synaptic plasticity and in behaviors such as learning and memory are not well understood. Here we report that postnatal forebrain deletion of Cdc42 leads to deficits in the synaptic plasticity and in remote memory recall using conditional knockout of Cdc42. Read More

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RESEARCH GROUP LEADERS

Dr. McLean Bolton

Disorders of Neural Circuit Function


Dr. Jason Christie

Mechanisms of Synaptic Signaling and Computation


Dr. David Fitzpatrick

Functional Architecture and Development of Cerebral Cortex


Dr. Hyungbae Kwon

Cellular Basis of Neural Circuit Plasticity


Dr. Bert Sakmann

Digital Neuroanatomy


Dr. James Schummers

Cellular Organization of
Cortical Circuit Function


Dr. Hiroki Taniguchi

Development and Function of
Inhibitory Neural Circuits


Dr. Ryohei Yasuda

Neuronal Signal Transduction


Dr. Samuel Young, Jr.

Molecular Mechanisms of
Synaptic Function