Ca2+-Dependent Modulation of Presynaptic Ca2+ Channels

Thursday, January 22nd, 2015, 11:00 AM
Elmore Auditorium
Amy Lee, PhD, University of Iowa
Samuel M. Young, Jr., PhD
(561) 972-9000

Event Information

Voltage-gated Cav Ca2+ channels mediate activity-dependent Ca2+ signals controlling neuronal gene expression and synaptic transmission. Cav channels are subject to diverse forms of modulation, including by Ca2+ ions that permeate the pore. A variety of  Ca2+ sensing proteins, including calmodulin, coassemble with Cav channel complexes and can boost or inhibit further Ca2+ influx. Our research aims to uncover the mechanisms controlling this feedback regulation of Cav channels by Ca2+, and their roles in neural circuits that are disrupted in neurological and neuropsychiatric disorders.

This seminar is open to faculty, scientists, and students from Max Planck Florida Institute for Neuroscience (MPFI), Florida Atlantic University (FAU), and the Scripps Research Institute Florida, located on FAU’s John D. MacArthur Campus in Jupiter, Florida. If you belong to an institution outside of the Jupiter campus and would like to attend, please send a request to seminars@mpfi.org