Experience-dependent synapse reorganization in the living brain

Thursday, April 23rd, 2015, 11:00 AM
Elmore Auditorium
Yi Zuo, PhD, UCSC
Ryohei Yasuda, PhD
(561) 972-9000

Event Information

2014-15 MPFI Seminar Series

One fundamental question in neuroscience is how the brain processes and stores information. As the information-processing elements in the brain, neurons communicate via specialized connections called synapses. The majority of excitatory synapses reside at dendritic spines, which serve as a good proxy for synaptic connectivity. Using in vivo two-photon imaging, our recent studies followed the dynamics of spines on apical dendrites of L5 pyramidal neurons in the living brain. In this talk, I will discuss our findings on 1) the spatiotemporal changes of spine dynamics during motor-skill learning; and 2) the molecular/cellular mechanisms underlying activity-dependent spine pruning during development.



This seminar is open to faculty, scientists, and students from Max Planck Florida Institute for Neuroscience (MPFI), Florida Atlantic University (FAU), and the Scripps Research Institute Florida, located on FAU’s John D. MacArthur Campus in Jupiter, Florida. If you belong to an institution outside of the Jupiter campus and would like to attend, please send a request to seminars@mpfi.org