Optogenetic tools to probe and manipulate protein interactions

Thursday, July 2nd, 2015, 11:00 am
Elmore Auditorium
Chandra L. Tucker, PhD, University of Colorado Denver, School of Medicine

Hyungbae Kwon, PhD
(561) 972-9000

Event Information

While optogenetic methods are now commonly used in neuroscience, we seek to expand the field to allow light control of a variety of basic molecular and cellular processes. Over the past several years, my lab has pioneered use of the Arabidopsis photoreceptor cryptochrome 2 (CRY2) as an optogenetic module. We have developed methods using CRY2 in conjunction with a binding partner, CIB1, for control of protein-protein dimerization, as well as ways to use CRY2 on its own. Here I will discuss the different ways we are using cryptochromes to probe, block, or induce changes in protein-protein interactions with light, allowing control of a variety of biochemical processes.

This seminar is open to faculty, scientists, and students from Max Planck Florida Institute for Neuroscience (MPFI), Florida Atlantic University (FAU), and the Scripps Research Institute Florida, located on FAU’s John D. MacArthur Campus in Jupiter, Florida. If you belong to an institution outside of the Jupiter campus and would like to attend, please send a request to seminars@mpfi.org