- The Institute
- Postdoctoral Fellow
Department: Taniguchi Lab
A postdoctoral position is available working in the laboratory of Hiroki Taniguchi Ph.D., a research group leader at the Max Planck Florida Institute (MPFI).
Essential Duties & Responsibilities
Our research focus is on understanding neural circuit development and function of inhibitory interneuron subtypes (see below). We are looking for highly motivated individuals who will enjoy the process to achieve a unique science and have a strong ambition to create trends of neural circuit research in the future.
Cortical inhibitory interneurons (INs) display diverse subtypes, which innervate distinct compartments (e.g., dendrites, somata, and axon initial segments) of excitatory principal neurons (PNs) and regulate various types of circuit operations. We have been interested in elucidating subtype-specific IN function and development. To address these questions, we employ mouse genetics, molecular biology, virology, and imaging techniques. We are working on following projects.
1) Molecular mechanisms underlying specification and circuit formation of chandelier cells (ChCs), which powerfully control action potential generation in PNs by innervating their axon initial segments. We have already identified several candidate genes that are preferentially expressed in ChCs. We are analyzing the function of these genes in vivo.
2) We have developed a novel genetic strategy, which enables us to label and manipulate IN subtypes sending inputs to PN subtypes. We will determine the spatial organization and function of IN subtypes in cortical microcircuits. We will also elucidate mechanisms underlying the organization of IN subtypes innervating area- and layer-specific PNs.
Taniguchi et al.,Neuron, 2011
Taniguchi et al.,Science, 2013
Taniguchi et al.,Front. Cell. Neurosci, 2014
Ishino et al., Journal of Neuroscie, 2017
Steinecke et al., eNeuro, 2017
Education and/or Experience
Applicants must have or be expected to receive a Ph.D.
Experience in in vivo imaging, molecular biology, and in utero
electroporation is preferred but not necessary.
- Complete CV including a publication list, experimental skills and contact information on 3 reference persons
- Description of current and previous research summary (1-2 page)
- Description of the reason why you apply and what you want to do (1-2 page)
A PDF should be sent to Hiroki Taniguchi, Ph.D. via e-mail, in addition to submitting materials using this website.
Contact prior to application is welcome.