Department: Taniguchi Lab
SummaryA postdoctoral position is available working in the laboratory of Hiroki Taniguchi Ph.D., a research group leader at the Max Planck Florida Institute (MPFI). Our research focus is on understanding development and plasticity of inhibitory interneuron subtypes (see below). We are looking for highly motivated individuals who will enjoy the process to achieve a unique science and have a strong ambition to create trends of neural circuit research in the future.
Essential Duties & ResponsibilitiesResearch Topics include –
Cortical inhibitory interneurons (INs) display diverse subtypes, which innervate distinct compartments (e.g., dendrites, somata, and axon initial segments) of
excitatory principal neurons (PNs) and regulate various types of circuit operations. We have been interested in elucidating subtype-specific IN development and
plasticity. To address these questions, we employ mouse genetics, molecular biology, virology, and imaging techniques. We are working on following projects. 1) Molecular mechanisms underlying specification and circuit formation of chandelier cells (ChCs), which powerfully control action potential generation in
PNs by innervating their axon initial segments. We have already identified several candidate genes that are preferentially expressed in ChCs. We are
analyzing the function of these genes in vivo. We have also begun to be interested in the chromatin dynamics during cell type specification. 2) We have developed a novel genetic strategy, which enables us to label and manipulate IN subtypes sending inputs to PN subtypes. We will determine the
spatial organization and function of IN subtypes in cortical microcircuits. We will also elucidate mechanisms underlying the organization of IN subtypes
innervating area- and layer-specific PNs. 3) The role and molecular mechanisms of structural plasticity in cortical interneurons.
Education and/or ExperienceApplicants must have or be expected to receive a Ph.D. Experience in in vivo imaging, molecular biology, chromatin biology, and in utero electroporation is preferred but not necessary.
Additional InformationPlease submit the following: 1. Complete CV including a publication list, experimental skills and contact
information on 3 reference persons
2. Description of current and previous research summary (1-2 page)
3. Description of the reason why you apply and what you want to do (1-2 page) In addition to completing the information on this site, a PDF should be sent to Hiroki Taniguchi, Ph.D. via e-mail. Contact prior to application is welcome.