James Schummers, PhD

James Schummers, PhD

Research Group Leader
Cellular Organization of Cortical Circuit Function

One Max Planck Way
Jupiter, FL 33458
(561) 972-9110

Researcher Bio

Dr. James Schummers was named an independent Research Group Leader at the Max Planck Florida Institute for Neuroscience in June 2010 and heads the Cellular Organization of Cortical Circuit Function research group. Dr. Schummers received his bachelor’s degree in Neuroscience from Oberlin College in Oberlin, OH, where he studied the effects of the neurotransmitter neuropeptide-Y on long-term potentiation (LTP) in the hippocampus. He then moved to Denver CO, where he studied the effects of alcohol on LTP in the Department of Pharmacology at the University of Colorado Health Science Center. He received a PhD in Systems Neuroscience at the Massachusetts Institute of Technology with the support of a Howard Hughes Pre-Doctoral Fellowship. His thesis work combined intracellular and extracellular single neuron recordings with optical imaging approaches to study the integration of synaptic inputs in the context of visual processing. His postdoctoral work, also at MIT, focused on single-cell resolution imaging to study the response properties of different classes of cells, including both neurons and astrocytes, in the visual cortex.

Selected Publications

  1. López-Hidalgo, M., Hoover, W.B., and Schummers, J. (2016). Spatial organization of astrocytes in ferret visual cortex. J. Comp. Neurol. 524, 3561–3576.

  2. Estrada, G., Beetle, C., Schummers, J. (2015). Simple method to improve spatial resolution for in vivo two-photon fluorescence imaging. Appl. Opt. 54, 10044-10050.

  3. Sharma, J., Sugihara, H., Katz, Y., Schummers, J., Tenenbaum, J., Sur, M. (2015). Spatial Attention and Temporal Expectation Under Timed Uncertainty Predictably Modulate Neuronal Responses in Monkey V1. Cereb. Cortex 25, 2894-2906.

  4. Lopez-Hidalgo, M., Schummers, J. (2014). Cortical maps: a role for astrocytes?. Current opinion in neurobiology 24, 176-189.

  5. Mao R, Schummers J, Knoblich U, Lacey CJ, Van Wart A, Cobos I, Kim C, Huguenard JR, Rubenstein JL, Sur M. Influence of a subtype of inhibitory interneuron on stimulus-specific responses in visual cortex. Cereb Cortex. 2012 Mar;22(3):493-508. doi: 10.1093/cercor/bhr057. Epub 2011 Jun 10.

  6. Jarosiewicz B, Schummers J, Malik WQ, Brown EN, Sur M. Functional biases in visual cortex neurons with identified projections to higher cortical targets. Curr Biol. 2012 Feb 21;22(4):269-77. Epub 2012 Feb 2.

  7. Malik WQ, Schummers J, Sur M, Brown EN. Denoising two-photon calcium imaging data. PLoS One. 2011;6(6):e20490. Epub 2011 Jun 7.

  8. Runyan CA*, Schummers J*, Van Wart A*, Kuhlman SJ, Wilson N, Huang ZJ, Sur M. (2010) Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex. Neuron 67(5):847-57.

  9. Stimberg M, Wimmer K, Martin R, Schwabe L, Mariño J, Schummers J, Lyon DC, Sur M and Obermayer K. (2009) The Operating Regime of Local Computations in Primary Visual Cortex. Cerebral Cortex 19(9):2166-80.

  10. Schummers J, Yu H, Sur M. (2008) Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex. Science 320:1638-43.

  11. Schummers J, Cronin B, Wimmer K, Stimberg M, Martin R, Obermayer K, Koerding K and Sur M (2007) Dynamics of orientation tuning in cat V1 neurons depend on location within layers and orientation maps. Frontiers in Neuroscience (published online 1 November 2007).

  12. Wang KH, Majewska A, Schummers J, Farley B, Hu C, Sur M, Tonegawa S (2006) In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. Cell 126:389-402.

  13. Mariño J, Schummers J, Lyon DC, Schwabe L, Beck O, Wiesing P, Obermayer K, Sur M (2005) Invariant computations in local cortical networks with balanced excitation and inhibition. Nat Neurosci 8:194-201.

  14. Schummers J, Mariño J, Sur M (2002) Synaptic integration by V1 neurons depends on location within the orientation map. Neuron 36:969-978.

  15. Schummers J, Browning MD (2001) Evidence for a role for GABA(A) and NMDA receptors in ethanol inhibition of long-term potentiation. Brain Res Mol Brain Res 94:9-14.

  16. Schummers J, Bentz S, Browning MD (1997) Ethanol’s inhibition of LTP may not be mediated solely via direct effects on the NMDA receptor. Alcohol Clin Exp Res 21:404-408.

  17. Colvin RA, Walker JP, Schummers J, Davis N (1996) Aging does not affect steady-state expression of the Na+/Ca2+ exchanger in rat brain. Cell Mol Neurobiol 16:11-19.

  18. Janapati V, Wu A, Davis N, Derrico CA, Levengood J, Schummers J, Colvin RA (1995) Post-transcriptional regulation of the Na+/Ca2+ exchanger in aging rat heart. Mech Ageing Dev 84:195-208.